Binding of Candida albicans to Human CEACAM1 and CEACAM6 Modulates the Inflammatory Response of Intestinal Epithelial Cells
ABSTRACT Candida albicans colonizes human mucosa, including the gastrointestinal tract, as a commensal.In immunocompromised patients, C.albicans can breach the intestinal epithelial barrier and cause fatal invasive infections.Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1; CD66a), CEACAM5 (CEA), and CEACAM6 (CD66c) are immunomod